Monday, March 30, 2015

[R998.Ebook] Ebook Download Gauge Mechanics, by L. Mangiarotti, G. Sardanashvily

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Gauge Mechanics, by L. Mangiarotti, G. Sardanashvily

This book presents in a unified way modern geometric methods in analytical mechanics based on the application of fibre bundles, jet manifold formalism and the related concept of connection. Non-relativistic mechanics is seen as a particular field theory over a one-dimensional base. In fact, the concept of connection is the major link throughout the book. In the gauge scheme of mechanics, connections appear as reference frames, dynamic equations, and in Lagrangian and Hamiltonian formalisms. Inertial forces, energy conservation laws and other phenomena related to reference frames are analyzed; that leads us to observable physics. Special topics on relativistic mechanics, geometric BRST mechanics frame-dependent quantization and others, together with many examples, are also dealt with.

  • Sales Rank: #7200724 in Books
  • Brand: Brand: World Scientific Pub Co Inc
  • Published on: 1999-02-15
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.75" h x 6.50" w x 1.00" l, 1.45 pounds
  • Binding: Hardcover
  • 355 pages
Features
  • Used Book in Good Condition

Review
"The book is well written and contains many new results in time-dependent mechanics, showing that the differences from the autonomous case are stronger than a first glance would indicate." Mathematical Reviews

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Sunday, March 22, 2015

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The Making of the Fittest: DNA and the Ultimate Forensic Record of Evolution, by Sean B. Carroll

DNA evidence not only solves crimes―in Sean Carroll's hands it will now end the Evolution Wars.

DNA, the genetic blueprint of all creatures, is a stunningly rich and detailed record of evolution. Every change or new trait, from the gaudy colors of tropical birds to our color vision with which we admire them, is due to changes in DNA that leave a record and can be traced. Just as importantly, the DNA evidence has revealed several profound surprises about how evolution actually works. 50 black-and-white illustrations and 8 pages of color

  • Sales Rank: #48033 in Books
  • Brand: Carroll, Sean B./ Carroll, Jamie W. (ILT)/ Olds, Leanne M. (ILT)
  • Published on: 2007-09-17
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.30" h x .90" w x 5.50" l, .58 pounds
  • Binding: Paperback
  • 304 pages

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6 of 6 people found the following review helpful.
The extra piece of the evidence for evolution
By John Salerno
I've read three or four other books that explore the evidence for evolution and in all of those books they cover the familiar areas of the fossil record, geographical distribution, etc. and sometimes briefly discuss molecular evidence, but "The Making of the Fittest" deals specifically with that area (as you can tell from the subtitle). The book is a fantastic exploration of how DNA (literally the text of the base pairs or the specific amino acids of a protein) provides incontrovertible evidence for evolution. To deny evolution after seeing some of the impressive examples in this book is a clear indication that the denial is based purely on theological grounds and certainly not scientific ones.

The book is divided as such:

Chapter 1: An introduction to what the rest of the book will be discussing. However, I would have preferred that this actually have been an introduction instead of being chapter 1, because it doesn't really get into the topic of the book so much as summarize what each of the following chapters will be about.

Chapter 2: A somewhat difficult chapter that deals with the math of evolution. I love math but I felt at times that Carroll was simply telling us what the results of particular equations mean, as opposed to explaining the math itself. I would like to have learned how to do the calculations myself in the event I need to present this evidence to someone else. At one point he uses a logarithm without even explaining how the equation works, so it raises the question of why he even bothered to show us the math at all if he wasn't going to explain it.

Chapter 3: This is where the book really hits its stride and doesn't slow down for several chapters. This chapter discusses specific genes in our DNA that have remained unchanged for billions of year, evidence that natural selection has worked to keep these genes in place because of their fundamental usefulness to life.

Chapter 4: An utterly fascinating chapter on how new genes have evolved in order to create new features across various species. In particular Carroll discusses color vision and the similarities/differences between species in the genes that affect vision in various animals.

Chapter 5: Yet another completely absorbing chapter on "fossil genes" -- genes that have mutated over time and have become inactive, yet still can be used to trace their heritage far back through the past.

Chapter 6: Discusses the phenomenon of evolution repeating itself when given the same set of selection pressures with which to work, and how different species have independently evolved similar (or the same) features as a result.

Chapter 7: Deals specifically with human issues such as the "arms race" between increasingly drug-resistant bacteria and human-created methods to deal with such germs.

Chapter 8: A discussion on how complex features (such as the eye) can evolve. Intelligent designers, pay attention!

Chapter 9: Carroll stops with the science at this point and in this chapter deals with the common arguments against evolution and the rational responses to these arguments.

Chapter 10: The final chapter discusses how acceptance of evolution is more than just a philosophical exercise but instead can help us shape the future of not only our species but of many other species on the planet (especially those on the verge of extinction because of human activity). Even though Carroll discusses things such as overfishing, overhunting, pollution, and global warming, I didn't get the impression that he tied all of this up neatly with the actual idea that accepting the truth of evolution can help us with these things.

A few complaints I had were that:

1. At some points the explanations got a little difficult to follow, and not so much because the science (or math) was over my head, but because Carroll didn't seem to fully explain what he was describing. I feel like it was a fault of the writing in certain sections.

2. There are many charts, graphs, and pictures, but they weren't all explained very well. For example, Figure 4.3 (DNA Typing and Hominoid Evolution) shows a comparison of junk DNA called "SINES" among various animals (Human, Bonobo, Chimpanzee, Gorilla, etc.), but for the life of me I couldn't figure out what I was looking at or how to read the lines. I got the general idea of what I was seeing, but the caption and even the text itself didn't seem to explain the figure very well.

3. A problem many authors, including Carroll, seem to have is the habit of summing up the topics they are about to discuss. Chapter 1 is mainly a setup for the rest of the book and the final part of it actually sums up what each of the following chapters will discuss. Furthermore, within each chapter Carroll also will sometimes close a section by describing what the next section will be about, or close a chapter by describing what the next chapter will be about. Personally, I find this kind of writing to be somewhat lazy. It contains no real content, no new information, and reads like filler. It's as if the authors are not confident enough to simply end a section or chapter as-is without resorting to some type of segue into the next part.

However, overall the book is a fantastic exploration of how DNA reveals the evidence for evolution across just about every species. If you've read other books about the evidence for evolution, chances are they dealt with a little of this material, but not as in-depth as Carroll's book does. I definitely recommend this book to complement those other books, because it deals thoroughly with the DNA record. You will be amazed to see how similar DNA is across various species, and equally amazed to see that it differs in exactly the ways we would expect it to differ if evolution is true.

2 of 2 people found the following review helpful.
Fantastic!
By Book Shark
The Making of the Fittest by Sean B. Carroll

Fantastic! An accessible book on genetics that hits all the right notes. Music to my ears. Beyond any reasonable doubt this is one of the best books to get on evolution. DNA contains the information that decisively confirms evolution. This book contains the information that makes it clear that it is so.

Positives:

1. Evolution explained for the general masses with focus on genetics.
2. Dr. Carroll uses a great approach to explain the complexities of genetics. Each of the 10 chapters begins with stating clearly what we are expected to learn from that chapter.
3. Some great examples and wonderful illustrations.
4. Great examples of evolution.
5. Some fascinating and memorable information.
6. Introduces new terms you have probably never heard, but will understand as a result of the author's innate ability to present in a clear manner.
7. Great civility used in debunking creationists misinformation on evolution.
8. Powerful and memorable arguments. Well reasoned and well thought out.
9. Covers many topics about evolution not just genetics.
10. There are many great books on evolution: "Why Evolution is True" by Jerry Coyne, "The Greatest Show On Earth" by Richard Dawkins, "Your Inner Fish" by Neil B. Shubin, "What Evolution Is" by Ernst Mayr and now "The Making of the Fittest" by Sean B. Carroll is also worthy of being on that top mantle of books about evolution.

Negatives:

1. It's not intended for those in the field due to its basic and general approach.
2. I wanted more...more examples.

In summary, a fabulous book on evolution that focuses on genetics. I can't recommend this book enough. Highly recommended to all those who want to learn about evolution but are too fearful that the topic may be way over their heads...no need to fear Dr. Carroll is here.

0 of 0 people found the following review helpful.
Best book on evolution that I've read
By andrew walter
This was a great book and helped me understand mutations within the framework of evolution much more clearly. By far it's probably my favorite and most informative book on DNA that I've read. If you are wanting to learn about how evolution through natural selection works I highly recommend this book!

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Wednesday, March 18, 2015

[P972.Ebook] Download Ebook Cystic Fibrosis in Adults, by James R. Yankaskas, Michael R. Knowles, Yankaskas

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Cystic Fibrosis in Adults, by James R. Yankaskas, Michael R. Knowles, Yankaskas

This volume links the very latest advances in cystic fibrosis research with clear, comprehensive, practical guidelines for the clinical care of adult CF patients. The book is unique in its focus on the symptoms, complications, treatment decisions, and quality-of-life concerns that arise after CF patients reach adulthood. Major sections cover the pulmonary disease and its complications, the gastrointestinal and nutritional problems associated with CF, and the other organ systems affected by CF. Coverage includes descriptions of molecular, cellular, tissue, and organ-level physiology and clinical manifestations of CF. Emphasis is on differential diagnosis, diagnostic approaches, current treatment options, and practical patient management recommendations. The book also includes chapters on reproductive issues, adult social issues, and the U.S. National Cystic Fibrosis Foundation

  • Sales Rank: #4128870 in Books
  • Published on: 1998-09
  • Original language: English
  • Number of items: 1
  • Dimensions: 10.50" h x 7.50" w x 1.25" l,
  • Binding: Hardcover
  • 528 pages

From The New England Journal of Medicine
Forty years ago, prospects were bleak for a patient with cystic fibrosis, which was then an invariably fatal disease of early childhood. Patients seldom survived beyond infancy; they succumbed to malnutrition and pulmonary complications. Nonetheless, a few centers initiated an aggressive, comprehensive approach to the care of patients with cystic fibrosis that introduced symptomatic treatments designed to slow the progression of the disease. Since that time, their clinical condition has improved. Although some patients still die early in life, many others live well into adulthood. Better diagnostic techniques and refinements of therapeutic strategies have combined to increase the median age of survival beyond 30 years. More than a third of all patients in the United States who are registered with the Cystic Fibrosis Foundation are older than 18 years of age. Cystic fibrosis has "grown up" and become a disease treated by internists as well as pediatricians.

Cystic Fibrosis in Adults discusses the advances and reviews extensively the clinical issues that are pertinent to patients with this disease. The first several chapters serve as an introduction and review the pathogenic mechanisms that may be potential targets of therapy. Along with improvements in the clinical care of patients with cystic fibrosis, our understanding of the molecular and cellular biology of the disease has expanded rapidly since the identification of the gene for cystic fibrosis 10 years ago. The physiologic and genetic information about the basic defect has provided valuable insight into the structure and function of the cystic fibrosis transmembrane conductance regulator and how mutations in the gene for this protein may contribute to the pathophysiology of the disease. This knowledge has led to a shift in the therapeutic approach to cystic fibrosis. Whereas previous therapies were directed at the downstream effects of the disease, new therapies are being designed to correct or bypass the basic defect.

Because more than 90 percent of patients with cystic fibrosis die from associated lung disease, much of the book is devoted to the pulmonary manifestations of cystic fibrosis. Several chapters discuss the current management of sinopulmonary disease in cystic fibrosis, which is directed primarily at the consequences of infection and inflammation, as well as the role of lung transplantation in end-stage disease. New approaches to treatment of pulmonary disease are also discussed, with a focus on the status of gene therapy for cystic fibrosis. Although this information may be useful to researchers, many of the details included in the discussion are probably irrelevant to clinicians. Less space is devoted to some of the newer, exciting pharmacologic therapies that may correct or circumvent the defective cystic fibrosis transmembrane conductance regulator. Many of these new drugs are now being used in patients, and I suspect that they would be of great interest to clinicians who care for adults with this disease. Indeed, these therapeutic strategies may deserve a chapter of their own.

The remainder of Cystic Fibrosis in Adults covers many of the extrapulmonary manifestations, with particular emphasis on the pancreatic and gastrointestinal complications of the disease. It also includes chapters on clinical topics that are neglected in other textbooks, such as reproductive issues in patients with cystic fibrosis.

Cystic Fibrosis in Adults clearly shows the symbiosis between research and clinical care with regard to the disease. The book is well organized, and the individual topics are covered thoroughly. Inevitably, as in any multiauthored book, there is some duplication of the information presented. Nevertheless, the editors have produced a useful reference book, and this comprehensive textbook integrates information on the care of patients with new insight into the pathogenesis of cystic fibrosis. As our understanding of the molecular and cellular basis of the disease advances, new therapeutic strategies will emerge that ideally will increase the life expectancy of patients even further. With luck, future editions will need to include a section on the geriatric care of patients with cystic fibrosis.

Reviewed by Thomas Ferkol, M.D.
Copyright © 2000 Massachusetts Medical Society. All rights reserved. The New England Journal of Medicine is a registered trademark of the MMS.

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1 of 1 people found the following review helpful.
Cystic Fibrosis in Adults [Illustrated] (Hardcover)
By DeanS
This is an incredible book that can assist any adult CF patient. The authors work in North Carolina at UNC and have an excellent grasp of the problems the disease has on parients and more importantly, they understand the progression in adults.

For someone looking to understand the reasons for the tests, and what the goals are in treating adult CF patients, this is the book to get.

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A Fast Track To Structured Finance Modeling, Monitoring and Valuation: Jump Start VBA, by William Preinitz

This book is designed to start with simple examples that progressively develop the reader's confidence to take on more complex tasks. There is very little theoretical discussion about computer science, operations research algorithms, mathematics, or finance. The thrust of the book is to teach the reader to break complex tasks down into simple tasks. It then looks to implement those simple tasks into VBA code using a critical subset of the features of the language.

The tentative contents is: (1) Why? What? Who? Where? and How? (2) Common Sense (3) Securitizing A Loan Portfolio (4) Understanding the Excel Waterfall (5) Designing the VBA Model (6) Laying the Model Groundwork (7) Recorded Macros: A First Look at the VBA Language (8) Writing Menus: An Introduction to Data, Ranges, Arrays, and Objects (9) Controlling the Flow of the Model (10) Building Messaging Capabilities (11) Designing the Model’s Reports (12) Main Program and Menus (13) Writing the Collateral Selection Code (14) Calculating the Cash Flows (15) Running the Waterfall: Producing Initial Results (16) Debugging the Model (17) Validating the Model (18) Running the Model (19) Building Additional Capabilities (20) Documentation of the Model (21) Managing the Growth of the Model (22) Building Portfolio Monitoring Model (23) Valuation Techniques: How do we Determine Price? (24) Challenging Times For the Deal (25) Parting Admonitions

  • Sales Rank: #102600 in Books
  • Published on: 2009-02-09
  • Original language: English
  • Number of items: 1
  • Dimensions: 10.10" h x 2.26" w x 7.36" l, 3.29 pounds
  • Binding: Hardcover
  • 744 pages

From the Inside Flap

An introductory work to structured modeling in Visual Basic Application (VBA), A Fast-Track to Structured Finance Modeling, Monitoring, and Valuation: Jump Start VBA provides you with a concise, immediate, and practical guide to developing a meaningful level of modeling expertise on problems in structured finance. Designed to allow you to cross from the pure Excel world to the much more powerful and flexible world of VBA/Excel, this straightforward book is built around a structured finance case study in asset-based securitization.

Starting with basic examples that progressively develop your confidence to take on more complicated tasks, this book teaches you how to break complex tasks down into simple tasks and then implement them into VBA code using a critical subset of the features of the language. This hands-on, step-by-step guide features coverage of:

  • General modeling concepts

  • The Cash Flow Waterfall in Excel code

  • Organizing and creating VBA modules to hold your model code

  • Generating VBA code from recorded macros, and how to simplify and extract it for use in your model

  • Efficiently using VBA statements to control the flow of the model

  • How to use template files for efficient and flexible report writing

  • Writing a collateral selection and reporting capability into your model

  • How to generate collateral cash flows on a loan-by-loan, period-by-period basis

  • Calculation optimization applied to collateral cash flow amortization

  • How to use the VBA debugger to detect and correct different types of errors

  • How to use the completed model to structure and size a finance deal

  • Modifying the model to allow multiple scenario runs

  • Protecting and evolving the model so it continues to create value for the business unit

  • How to add additional reporting and analytical features to the existing model

  • How to convert the structuring model into a monitoring and valuation model

  • Allowing for the use of monthly empirical performance information

  • Use of the monitoring and valuation model to track the performance of the deal

  • Valuing the deal based on its performance, market conditions, and rating criteria

Accompanied by an online resource containing a complete working model and all the data and files professionals need to run it, A Fast-Track to Structured Finance Modeling, Monitoring, and Valuation: Jump Start VBA is the only book written for the complete novice, enhancing your ability to break complex, seemingly insoluble problems down into a set of manageable tasks, through the use of VBA.

From the Back Cover
A straightforward, how-to guide to the fundamentals of finance modeling

"This book is a complete, all-in-one toolkit for structured finance modeling with Excel VBA, written by a veteran of a leading Wall Street investment bank who is also a VBA instructor. Whether you are new to structured finance or a seasoned professional, you will find here all you need to model even the most complex structured finance transactions. The book and accompanying web site provide the theory, the organization, and the code itself that take you step-by-step through the entire process, right up to the tasks market participants are most focused on today: valuation and monitoring. In addition to the nuts and bolts, you will find explanations and insights that only an experienced structured finance banker can provide. This book is the definitive resource that will raise you above the competition in modeling structured finance transactions."
—Carol Childers, Director, Global Markets, Citigroup

"Learning VBA is a daunting undertaking, add to that the challenge and complexity of structured cash flows, and the task can become overwhelming. This book provides a great step-by-step approach to overcoming this hurdle. It is extremely easy to read and offers a deliverables checklist for each chapter to ensure all concepts have been understood before moving on. The reader comes away with not only a sense of the utility and flexibility of VBA but also a sense of the factors that play into structuring cash flows. Concepts that are extremely pertinent in today's market environment include the performance of collateral, pricing of securities, and impact of the economic environment on the cash flows available to investors and all interested parties."
—Kimberly Brown, Analyst, Commercial Real Estate, Citigroup

"Bill is extraordinarily methodical in real life, with a very wide view of life. This shows in his book. Rather than rush through the ins and outs of code, he emphasizes what is needed, why it is needed, and how it is used. This makes the book much more than just a book on financial models, and closer to a book on how to be a financial professional."
—Omar Haneff, Vice President, Proteus Technologies LLC

About the Author

William Preinitz is a Managing Director with Citigroup Global Markets' Global Special Situations Group. He oversees new business origination-structured finance issuance, serv-icing operations, rating agency relationships, credit wrap providers, investors, analytical development, internal risk control, audit activities, hedging, and residual arbitrage activities.

Most helpful customer reviews

0 of 0 people found the following review helpful.
Great Book for Learning VBA but Final Model Is Not Correct
By GCR
I purchased this book a few years ago, so I am a little late to the review process. I did have a fair Excel/VBA knowledge base and an above average Structured Finance background, so this book provided good information for someone looking to upgrade their VBA skills. One word of warning though, make sure you read and execute all of the chapters and associated models and not just use the final model at the end as your own...there is an error in the code described in the book when calculating the floating rate bond principal and will give you an incorrect collateral amortization schedule. If used as a pure VBA learning tool this book is well above average.

3 of 3 people found the following review helpful.
Great book, better than any other structured fin. book
By Ju1ce
My desk needed me to create a model to value/monitor our retained MSR portfolio. After quickly reading through 3 books(this one, the excel one, and the OOP one) I decided this book best suited our needs. Hands down this book delivered the best model by the end. But as the other reviewer said, this does take some time, even when using the example model he provided on the webpage.

Needless to say, my boss seemed very impressed by the model I was able to produce with this book. Would recommend to anyone at any capacity.

This was my first CF model. I have little prior knowledge of finance, and strong knowledge of VBA & Math. Took me roughly 8 weekends or so.

14 of 17 people found the following review helpful.
Good knowledge, though a bit misleading
By Sau Yen Hom
I purchased this book having already a working knowledge of Visual Basic. I wanted basically what the title suggested, a fast track into the interconnected world of VBA and Finance. First, a note to those who are thinking about buying this: You will have to put time into this book. You cannot just sit on your bed and casually read it from cover to cover. The web site and this book go hand-in-hand together, and even if you ignore that portion (not recommended), you will need to have Excel open through some of the chapters or you will not get much out of it. Therefore, this book is for those who are dedicated to really learning how financial modeling works, and not just for people who want to read up on VBA code.

Pros: What everyone is saying: This guy knows what he's doing and what he's talking about. He provides great background information in the first three chapters. As a person with programming background, the pace felt really slow in the first couple of chapters as he walks you through the concepts. He also provides information about the nature of the project you will be working on. Overall, the pacing feels off, but if you're patient you won't find this a problem.

Cons: Those who fancy ourselves programmers remember our first lesson: the "Hello World" example. It was basically to introduce us to very elementary code. This is exactly what he does starting around chapter 7. He tells you to do something small and insignificant so you get a feel for how macros work and a glimpse at the resulting code. However, he then ramps up the difficulty by "cleaning" up the code. Here he starts slapping on and stripping syntax in such a way that someone who has little background in programming would get lost. This is by no means game-breaking but even I sometimes found myself staring at the "revised" code for a good 10-15 minutes trying to figure out what exactly he did. The statement he makes that this book was intended for those who know nothing of VBA is therefore misleading; he introduces a lot of syntax and code without truly explaining their nature. Again, to someone with some background in programming this is just a small nuisance you can work around. To someone that knows nothing, this is a serious hurdle. Another minor issue is that the book contains several typos. Not huge, but a lot of these typos are ridiculous mistakes that should easily have been caught by any editor.

In conclusion, this is a great book if you have a working knowledge of programming. Otherwise, you may get lost in the moments where he just spits language at you without explaining them. Beginners can probably turn to Power Programming to start off.

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  • Sales Rank: #1204936 in Books
  • Published on: 2016-12-25
  • Original language: English
  • Dimensions: 9.00" h x .23" w x 6.00" l,
  • Binding: Paperback
  • 98 pages

Most helpful customer reviews

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  • Sales Rank: #18102466 in Books
  • Published on: 2000-10
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.00" h x 7.50" w x .25" l,
  • Binding: Paperback
  • 160 pages

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Kimberlites: Mineralogy, Geochemistry, and Petrology, by Roger H. Mitchell

This is a book about the petrology of kimberlites. It is not about upper mantle xenoliths, diamonds, or prospecting for kimberlites. The object of the book is to provide a comprehensive survey and critique of the advances which have been made in kimberlite studies over the last twenty-five years. Kimberlites are rare rock types; however, their relative obscurity is overriden by their economic and petrological importance to a degree which is not shared with the commoner varieties of igneous rocks. Kimberlites are consequently of interest to a diverse group of earth scientists, ranging from isotope g~ochemists concerned with the evolution of the mantle, to volcanologists pondering the origins of diatremes, to exploration geologists seeking new occurrences of the diamondiferous varieties. A common factor essential to all of these activities is a thorough understanding of the characteristics of kimberlites. For the petrologist, kimberlites are exciting and challenging objects for study. Their petrographic diversity, complex mineralogy and geochemistry, and unusual style of intrusion provide endless opportunities for stimulating hypothesis and conjecture concerning their origin and evolution. Kimberlites are a part of a wide spectrum of continental intra-cratonic magmatism. Only by understanding all of the parts of this activity in detail may we make progress in our understanding of the whole.

  • Sales Rank: #5479010 in Books
  • Published on: 1986-04-30
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.21" h x 1.06" w x 6.14" l, 1.81 pounds
  • Binding: Hardcover
  • 442 pages

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